Institutional Ownership

Top Holders

Holder Shares Held % O/S Share Change Filing Date
Roivant Sciences Ltd. 18,577,380 25.20 -- 7/31/21
Suvretta Capital Management, LLC 5,914,000 8.02 -- 3/31/22
Rubric Capital Management LP 3,000,000 4.07 -- 3/31/22
The Vanguard Group, Inc. 2,098,581 2.85 -50,571 3/31/22
Hudson Bay Capital Management LP 1,682,000 2.28 -118,000 3/31/22
Cladis Investment Advisory, LLC 1,126,000 1.53 22,000 3/31/22
SV Inflections GmbH 841,371 1.14 841,371 6/30/21
Medical Strategy GmbH 740,190 1.00 205,000 12/31/21
Prosight Capital 670,300 0.91 -131,880 3/31/22
Renaissance Technologies LLC 567,153 0.77 -86,547 3/31/22

Top Holders: Mutual Funds

Fund Shares Held % O/S Share Change Filing Date
Vanguard Total Stock Market Index Fund 1,382,708 1.88 -- 3/31/22
SV Inflections Fund FCP-RAIF 841,371 1.14 841,371 6/30/21
Vanguard Extended Market Index Fund 593,038 0.80 -- 3/31/22
MEDICAL BioHealth 461,897 0.63 148,000 12/31/21
Bridgeway Ultra-Small Company Market Fund 329,300 0.45 -69,000 12/31/21
Fidelity Extended Market Index Fund 273,214 0.37 -- 3/31/22
DFA U.S. Small Cap Portfolio 209,862 0.28 51,387 1/31/22
APO Medical Opportunities 166,593 0.23 -- 9/30/21
iShares Micro-Cap ETF 123,098 0.17 -728 4/30/22
RIM Global Fund Bioscience 111,700 0.15 57,000 12/31/21

* Insider values reflect direct beneficial ownership.

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