Institutional Ownership

Top Holders

Holder Shares Held % O/S Share Change Filing Date
Roivant Sciences Ltd. 18,577,380 31.62 5,333,333 2/24/20
Consonance Capital Management LP 3,186,335 5.42 -50,000 12/31/20
Rubric Capital Management LP 2,500,418 4.26 165,218 3/31/21
Opaleye Management Inc. 2,000,000 3.40 -39,100 12/31/20
Hudson Bay Capital Management LP 1,600,000 2.72 -- 3/31/21
The Vanguard Group, Inc. 1,027,290 1.75 -74,060 3/31/21
Medical Strategy GmbH 535,190 0.91 -- 1/31/21
Renaissance Technologies LLC 481,707 0.82 481,707 3/31/21
Sio Capital Management, LLC 460,248 0.78 -426,417 3/31/21
Morgan Stanley & Co. LLC 349,454 0.59 348,124 12/31/20

Top Holders: Mutual Funds

Fund Shares Held % O/S Share Change Filing Date
Vanguard Total Stock Market Index Fund 986,282 1.68 -- 3/31/21
MEDICAL BioHealth 313,897 0.53 -- 1/31/21
APO Medical Opportunities 166,593 0.28 -- 9/30/20
Pengana High Conviction Equities Fund 65,438 0.11 -- 5/31/20
Delaware Healthcare Fund 64,171 0.11 -- 3/31/21
RIM Global Fund Bioscience 54,700 0.09 -- 1/31/21
Fidelity NASDAQ Composite Index Fund 47,869 0.08 -- 3/31/21
Vanguard Institutional Total Stock Market Index Fund 40,650 0.07 -- 3/31/21
PRIMECAP Odyssey Aggressive Growth Fund 39,325 0.07 -300 3/31/21
apo Medical Opportunities Institutionell 27,478 0.05 -- 3/31/21

* Insider values reflect direct beneficial ownership.

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